Today's seminar is a
combined MHTP Infectious and Inflammatory Diseases Theme Seminar
A light lunch is served prior to the seminar at 11:45am in the
seminar room foyer, level 2, TRF Building.
Further information available from CID Weekly Seminar Series website[http://www.med.monash.edu.au/scs/medicine/cid/seminar-series.html]
Ischemia, immunosuppression and infection -
Tackling the predicaments of post-stroke complications
Dr Connie Wong
Heart Foundation Future Leader Fellow
Centre for Inflammatory Diseases
The incidence of stroke has risen over the
past decade and will continue to be one of the leading causes of death and
disability worldwide. While a large portion of immediate death following stroke
is due to cerebral infarction and neurological complications, the most common
medical complication in stroke patients is infection. Recent evidence suggests
that the disrupted interplay between the central nervous system and immune
system contributes to the development of infection after stroke. The
suppression of systemic immunity by the nervous system is thought to protect the
brain from further inflammatory insult, yet this comes at the cost of increased
susceptibility to infection after stroke. In the talk, I will be outlining our
recent work in this field, including identification of the source of infection
and potential targets for therapy.
Connie completed her Honours and PhD studies at
MIMR (now Hudson Institute) and graduated in 2008. Her postdoctoral training was at
University of Calgary, under Prof. Paul Kubes, a prominent figure in
intravascular immunity research. During this time, she made important
discoveries that resulted in a number of high-impact publications. Upon her
return to Australia, she was awarded ARC DECRA fellowship. She is currently
funded by the Heart Foundation Future Leader Fellowship and the leader of the
Neuroinflammation Research Group at the Centre for Inflammatory Diseases (CID),
where she runs her own independently funded research team.
Flyer attached here.
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