Tuesday, 27 June 2017

Monash stroke researcher awarded prestigious Club Melbourne Fellowship

The Honourable Linda Dessau AC, Governor of Victoria and
Associate Professor Dominique Cadilhac
Associate Professor Dominique Cadilhac from the School of Clinical Sciences at Monash Health (SCS) was awarded the highly regarded Club Melbourne Fellowship at a ceremony in Melbourne last week.

Presented by The Honourable Linda Dessau AC, Governor of Victoria, the Fellowship gives Associate Professor Cadilhac access to the exclusive Club Melbourne Ambassador Program network as well as a $10,000 grant to support attendance at international conferences to enable new research opportunities. 

The prestigious Fellowship recognises excellence in research, innovation and leadership, and is designed to support high-quality Melbournian research projects and the next generation of potential Club Melbourne Ambassadors. This is the second time in the 12 years of the Club Melbourne initiative that this Fellowship has been offered. Club Melbourne is designed to harnesses the passion of Melbourne’s elite thinkers from diverse fields with a common goal to contribute to Victoria's economic growth and international reputation.

Head of the Translational Public Health and Evaluation Division, Stroke and Ageing Research at Monash University, Associate Professor Cadilhac is an expert in health services research related to stroke, particularly in the areas of economic evaluation and program evaluation.

With a clinical background in nursing, Associate Professor Cadilhac has over 130 journal publications and has contributed to eight practice guidelines. She is best known for establishing the Australian Stroke Clinical Registry and the Victorian Stroke Telemedicine Program and heads up these programs in a collaborative role with the Florey Institute of Neuroscience and Mental Health.

Associate Professor Cadilhac said she is very proud to have been nominated by The Florey for this prestigious fellowship which will allow her to advance efforts to undertake high quality economic evaluations of interventions in the area of stroke and promote the use of data from clinical quality registries to improve care and patient outcomes.

“I was thrilled and overwhelmed by the tremendous feedback and the recognition of my efforts in advancing health services research and economic evaluation in stroke care,” Associate Professor Cadilhac said.

“As a Club Melbourne Fellow, I will be able to work directly with key opinion leaders in my field from different countries, enhancing my international collaborations” she said.

Monash Haematology research recognised at Lugano Biennial International Lymphoma Conference

Professor Stephen Opat
Research at Monash Haematology was recognised at the 14th International Conference on Malignant Lymphoma held in Lugano, Switzerland last week, attended by more than 3000 international delegates.

The event is the premier scientific meeting for haematologists, oncologists, radiation oncologists, paediatricians, pathologists and leading researchers involved in the study and treatment of lymphoma.

Monash clinicians and researchers had four abstracts including three oral presentations and one poster.  A landmark chemotherapy-free study in follicular and aggressive B cell lymphoma was one of only three abstracts selected for presentation at the plenary session. The study examined the activity of Tazemetostat, a first-in-class, oral inhibitor of EZH2, an enzyme involved in reading of the DNA code.

“The long strands of DNA in the cells are tightly coiled around proteins called histones. However, DNA needs to be uncoiled to be read by the cell’s machinery. The EZH2 enzyme adds a mark to the histones which stops the DNA from uncoiling. The enzyme can be abnormally activated in several cancers including lymphoma, breast, prostate, melanoma, and bladder cancer. Tazemetostat can inhibit the EZH2 enzyme thus enabling the cells to read the DNA once more”, Professor Opat said.

Responses were seen in 92% of patients with relapsed follicular lymphoma and 29% with relapsed aggressive B cell lymphoma who had an abnormally activated EZH2. The Tazemetostat tablets were extremely well tolerated with few side effects.

Other presentations highlighted the clinical activity of ‘BGB-3111’, a next generation inhibitor of the Bruton Tyrosine Kinase enzyme in patients with chronic lymphocytic leukaemia and Waldenström’s macroglobulinemia.

Haematology Research is conducting further studies with these agents in the Monash Health Translation Precinct Clinical Trial Facility.

BMedSc(Hons) Information Night RESCHEDULED to 18 July at MMC

2017 BMedSc(Hons) cohort at SCS
Enhance your MBBS experience and get into research! Give yourself career options with Honours in the School of Clinical Sciences at Monash Health (SCS).

This event has been postposted and is now scheduled on: Tuesday 18 July, 5.30pm-7.30pm
Seminar Rooms 1 & 2, Translational Research Facility (TRF), Monash Medical Centre

More information: HERE.
Please register: HERE

SCS / Hudson 3MT finals Friday 30 June

Please register to attend the SCS/Hudson 3MT finals and support your fellow students who will be presenting next Friday 30th June.

Last year one of our own students went on to compete in both the Faculty Heat and the Monash Finals and won People's Choice.

Registration is essential for catering purposes on the following link by Thursday 29 June: https://my.monash.edu.au/news-and-events/bookings/mmcbs/view/207305/

Save the date! Translational Research symposium at Monash University 31 July

Translational Research skills have become an important part of life at Monash's three metropolitan clinical schools. Significant findings and discoveries made in the lab can often get lost in their conversion to clinical practice and everyday medical treatments.

Central Clinical School is hosting a Translational Research symposium on 31 July 2017. All welcome to hear from top Melbourne-based researchers with national and international collaborations in clinical areas. See speaker program and RSVP at: http://www.med.monash.edu.au/cecs/events/2017-tr-symposium.html
    See more about what we have to offer in Translational Research:

MHTP Technology Platform Expo 13 July


All staff are invited to Meet the Dean at the SCS Faculty Staff Forum.

Tuesday 25 July, 4.30-6.30pm
Seminar Rooms 1 & 2, TRF, MHTP

The purpose of this Forum is to meet with the Dean and Senior Faculty Staff and learn of recent important Monash University and Faculty developments, and to engage with other Senior Faculty colleagues. This is also an opportunity for senior staff to discuss with Faculty Senior Management potential opportunities and local concerns, and to provide feedback to the Faculty.

Grant Review Panels (GRPs) for SGS 2018 - general

The Faculty Research Office is seeking researchers (including Early Career Researchers) and clinicians to serve on grant review panels (GRPs) for the SGS 2018 scheme between 29 September and 29 October, 2017. Review and assessment of applications will be conducted online at the SGS 2018 (FluidReview) website. If required, a face-to-face panel meeting is arranged by the Panel Chair between 30 October and 10 November 2017.

Since it is a condition of award that applicants agree to serve on future GRPs, we expect that awardees from earlier rounds will be well represented on the SGS 2018 panels. Panel member availability, role type, nominated grant category, School/Department, and areas of expertise are carefully considered in the final selection of panel members.

The information that we require from prospective panel members is listed below:

a)  The role in which you would classify your panel membership:
·  Researcher
·  Early Career Researcher
·  Clinician

b)  The category of panel on which you would like to serve:

Strategic Project Grant (SPG) - [Lab]
Strategic Project Grant (SPG) - [Non-Lab]
Early Career Development Grant (ECD) - [Lab]
Early Career Development Grant (ECD) - [Non-Lab]

c)    Areas of expertise
Please briefly outline (dot points only) your areas of research expertise and provide your School/Department. While every effort is made to match your review assignments with your area of expertise panel assignments are dependant on the pool of applications received. 

Please advise the Faculty Research Office (medicine.research@monash.edu) of your availability and preferred grant category by no later than Friday 21 July 2017.  

Hudson Seminar Series - "Mitochondrial DNA, why bother?", 29th June

This week's Hudson Seminar will be held, Thursday 29th June at 12:00pm-1:00pm in Seminar rooms 1 & 2, Level 2, TRF Building.
The speaker will be Professor Jus St. John, Head of the Centre for Genetic Disease and Group Head Mitochondrial Genetics Group, Hudson Institute of Medical Research.

A light lunch and refreshments will follow the presentation. 
Jus St. John’s research focuses on understanding how mitochondrial DNA is transmitted and replicated. Using a variety of assisted reproductive technologies and embryonic and cancer stem cell models, he has described mitochondrial DNA replication events in oocytes, embryos and undifferentiated and differentiating cells and why they are important to developmental outcome. He has also shown how mitochondrial DNA copy number is regulated in a cell-specific manner by DNA methylation of the nuclear-encoded mitochondrial DNA-specific polymerase; and how mtDNA haplotypes influence chromosomal gene expression patterns. He is using these outcomes to develop mini-pig models of autologous mitochondrial supplementation to enhance developmental outcomes and other assisted reproductive strategies to regulate the transmission of mitochondrial DNA from one generation to the next. He has published in The Lancet, Nature Chemical Biology, Nature Cell Biology, Nucleic Acids Research, Stem Cells, Cell Death and Differentiation, Journal of Cell Science, and Genetics. In 2013, he received the Society for Reproductive Biology’s Award for Excellence in Reproductive Biology Research.

PhD Final review milestone, Maciej Szarek, "Delineating the role of activin A targets in men's reproductive health", 3 July

All staff and students are invited to attend Maciej Szarek's PhD milestone review.

1pm, July 3rd, Hudson Boardroom.

Title:  Delineating the role of activin A targets in men's reproductive health 

Synopsis:  Reproductive health is an important aspect of men’s overall wellbeing, however, 1 in 20 men exhibit subfertility, which is associated with a higher risk of developing testicular cancer. A tightly regulated balance between somatic and paracrine signals mediates the appropriate timing of gonocyte maturation, of which members of the TGF-beta superfamily are substantially involved. Thus, my project investigates the hypothesis that a particular member of this superfamily, activin A, alters the level of chemokines (CXCL12, CCL17) and metalloproteinases (MMP2, MMP9) to mediate gonocyte cell fate choice, with aberrant production of these factors potentially contributing to testicular germ cell tumour development

Supervisors: Prof. Kate Loveland, A/Prof. Mark Hedger, Prof. Martin Bergmann
Panel Chair: Dr. Craig Harrison 

Independent assessors:  Dr. Patrick Western, Dr. Peter Stanton 

Monash Haematology Journal Club: “Catheter directed thrombolysis for DVT in the prevention of PTS”, 28 June

7.30am Breakfast & 7.45am Presentation
Monash Medical Centre, Level 2 - Lecture Theatre 3

“Catheter directed thrombolysis for DVT in the prevention of PTS”

Presenter: Dr Agnes Yuen  

MHTP Bioinformatics seminar: "Discover interferon (IFN) regulated genes using the INTERFEROME online database", Wed 28 June

Wed 28 June, 2pm-3pm - Hudson Institute Level 3 - Board Rooms

IFNs were identified as antiviral proteins more than 50 years ago and since then have been shown to regulate cell proliferation, survival, migration and specialised functions. Consequently they are involved in numerous homeostatic and pathological processes including infections, cancer, autoimmunity, inflammation and metabolic disorders. These cytokines are also used as therapeutics in diseases such as chronic viral infections, cancer and multiple sclerosis. IFNs potentially regulate the transcription of up to 2000 genes in an IFN subtype, dose, cell type and stimulus dependent manner. 

The Interferome database integrates information from high-throughput experiments to gain a detailed understanding of the various IFN activated pathways that regulate subsets of genes, with the aim to enhance our understanding of pathophysiological processes.

In this seminar Dr Ross Chapman, from the Centre for Innate Immunity and Infectious Diseases, will introduce you to the Interferome online database and demonstrate analysis tools available on this application.

For more information or to join the bioinformatics affinity group please contact: roxane.legaie@monash.edu 

Next Big Idea Award - attention ALL PhD students and ECRs

In under four minutes, pitch your Next Big Idea for commercialising research to a panel of industry and academic experts.
$2,200 prizes to be awarded for commercial potential and innovation.
·         Learn about biomedical research commercialisation
·         Fast track your career
·         Network with other entrepreneurs
·         Help patients
Information Session: Monday, 10 July, 1.30-3.30pm, Translational Research Facility, Level 2, Seminar Room 3.  This session will be recorded for students and ECRs unable to attend in person.
Preparatory Workshop
Friday, 28 July, 10am, Hudson Institute building, Level 3, Boardroom A&B.
To participate in the workshop, registration is essential.  See the Next Big Idea Award Guidelines.
Pitch Day
Thursday, 17 August, 2-4pm, Translational Research Facility, Level 2, Seminar Rooms 1&2.
Competition and Awards.

SCS ECR Mentor Program Applications EXTENDED to Friday 30 June 2017

Applications for the mentoring program are due this Friday.   We have many senior researchers that have volunteered to participate as mentors. 

If you have a researcher in mind that you would like as your mentor we can specifically contact that person.

Please read through the attached booklet (HERE) and complete the sections on pages 16 - 18 of the booklet:
'For Mentees' and 'Initiation Questionnaire'

Return application forms to aimee.dordevic@monash.edu OR xin.du@monash.edu

If you have previously participated in the mentor program we would really appreciate your feedback (5 - 10 minutes maximum), please use the following link:   

The Jack Brockhoff Foundation Medical Grants - CALL FOR EXPRESSIONS OF INTEREST (EOI)

The Jack Brockhoff Foundation invites applications for its Early Career Research Grants. Grants are worth up to AUD $70,000 each per year for one or two years. Applicants must have been engaged in full-time research for less than three years since completing their PhD.

These grants support Victorian research in health and well-being by helping to establish the careers of young scientists. They enable early-career researchers to demonstrate their scientific originality and their capacity to complete, with relative independence, a discrete study for publication in the scientific literature.

As Monash may only submit a maximum of two applications across the University (including from our affiliates), there will be an expression of interest (EOI), review, and ranking process for applications.

Intending applicants are required to prepare an EOI using the attached template HERE and submit it to the Faculty Research Office (medicine.research@monash.edu) by no later than 5:00PM (AEDT) on Monday 3 July 2017.

Applicants will be notified whether they have been selected to proceed to full application on or soon after 17 July 2017.

Final applications are due to the Jack Brockhoff Foundation by 5pm Wednesday 31 July 2017.

Further information on this scheme can be found at the following link and in Research Professional.

ECR event - lunch with Prof. Rosemary Horne, 12 July

Prof Rosemary Horne
Professor Rosemary Horne is a Deputy Director of the Ritchie Centre and the SCS Career Officer. She offers personalised advice on CV planning, grant and fellowship writing and other career advice. 

Come to the lunch to meet her and find out what she may offer. Lunch will follow a brief talk by Prof Horne, who will be there to have a chat.

Time: Wednesday 12th of July, 12:00pm - 1:00pm
Place: Level 7, TRF, breakout area

Lunch is provided!

Places are limited, please book using the link below:

Safety alert at MMC

Last week a staff member was robbed while walking along Wright Street to the carpark.  The incident took place at 4pm.

What do I need to look for?
·         Staff who walk in streets immediately surrounding MMC should be aware of their surroundings and be alert for suspicious people or vehicles in the area.
·         Where staff are concerned about a suspicious person or vehicle they should contact the Police directly on 000.

What about safety?

We take this opportunity to provide some personal safety strategies
·         Be alert for suspicious people or vehicles as you walk in the streets
·         Avoid talking on your mobile phone whilst in public
·         Avoid providing personal information to strangers
·         Always walk confidently and with purpose
·         Walk in groups where possible
·         Carry your car keys in your hand for quick access to your vehicle, without fumbling in your bag.
·         Use the Monash Health Shuttle bus to travel between MMC and the Browns Road South staff car park from outside E Block between 3:10pm and 7:55pm and 6:25am – 9:15am weekdays.
·         In an Emergency contact the Police directly (telephone 000)
·         Contact MMC Security (959 42139) at any time if you require assistance on Monash Health Properties
·         Remove Employee identification when you leave your workplace (eg: name badge, ID/Access card)
There are also strategies to consider inside our workplace
·         Be alert for suspicious people in the workplace
·         Secure personal belongings at all times
·         Avoid leaving money or valuables unattended
·         Avoid giving personal details or business information to strangers
·         Report any suspicious persons or incidents to MMC Security (959 42139)

How do I get more information or report a concern?

·         For Emergency assistance outside Monash Medical Centre please contact the Police on emergency number 000.
·         For assistance within Monash Medical Centre grounds please contact MMC Security on 959 42139.
·         For Emergency assistance within Monash Medical Centre or Monash Children’s Hospital please call the internal emergency number 999 and state your emergency.

For general enquiries regarding Monash medical Centre or Monash Children’s Hospital please contact Site Management
·         Telephone:         959 44727      

·         Email:                 MMCSiteManagement@monashhealth.org

Doctors push for review as stillbirth rates higher among South Asian, African women

Shavi Fernando reported on SBS news.  Watch story HERE.

New pancreatic cancer treatment showing promising signs of shrinking tumours

Marion Harris reported on Channel 9 news. Watch story HERE.

Scientists hope new take on old method will boost the chances of pancreatic cancer patients

Brendan Jenkins and Daniel Croagh reported in The World Today.  Listen to story HERE.


Dominique Cadilhac reported on 2SER.  Listen to story HERE.

South Asian, African-born women at greater risk of stillbirth than those born in Australia, study shows

Miranda Davies-Tuck reported on ABC news.  Read story HERE.

Pharmacokinetic modelling of modified acetylcysteine infusion regimens used in the treatment of paracetamol poisoning

Anselm Wong, Andis Graudins et al. published in the European Journal of Clinical Pharmacology.

Read article here.

Primary Intestinal Lymphangiectasia as a First Manifestation of Tuberous Sclerosis Complex

Rupert Hinds et al. published in the Journal of Pediatric Gastroenterology and Nutrition.

Read article here.

Impact of online toxicology training on health professionals

Anselm Wong et al. published in Clinical Toxicology.

Read article here.

The North American Neuroendocrine Tumor Society Consensus Guidelines for Surveillance and Medical Management of Midgut Neuroendocrine Tumors

Eva Segelov et al. published in Pancreas.

Read article here.

Herpes simplex virus-2 transmission following solid organ transplantation: Donor-derived infection and transplantation from prior organ recipients

Tony Korman et al. published in Transplant Infectious Disease.

Read article here.

The intensive care delirium research agenda: a multinational, interprofessional perspective

Yahya Shehabi et al. published in Intensive Care Medicine.

Read article here.

The Relationship between Dietary Intake, Growth, and Body Composition in Inborn Errors of Intermediary Protein Metabolism

Helen Truby et al. published in The Journal of Pediatrics.

Read article here.

Survival in Out-of-hospital Rapid Sequence Intubation of Non-Traumatic Brain Pathologies

Gabriel Blecher et al. published in Prehospital Emergency Care.

Read article here.

Long-term follow-up of the potential benefits of early nutritional intervention in adults with upper gastrointestinal cancer: a pilot randomised trial

Terry Haines, Helen Truby et al. published in Supportive Care in Cancer.

Read article here.

Monday, 19 June 2017

End of Financial Year: Payroll processing activities and impact on regular payroll deadlines

As the Monash HR’s Payroll Services team prepares for the end of financial year processing, we’d like to take the opportunity to highlight some changes impacting the regular payroll processes outlined below:
Final salary payments for the 2016/17 financial year
  • The final salary payment for 2016/17 financial will be paid on Thursday 22 June.
  • Salary payments processed after 22 June will be included in the payment summary for the following financial year (2017/18)
Timesheet approval deadlines
  • There are no changes to timesheet approval deadlines, however, timesheets not fully approved by Monday 19 June will not be paid until the next available pay period on Thursday 6 July.
Changes to the offline payment cycle
As a result of end of financial year associated activities (including the production of payment summaries) there will be no offline payments on Friday 23 June 2017 or Tuesday 27 June 2017.
The next available offline payment day is:
  • Friday 30 June – Requests for offline payment(s) must be received by 10am on Thursday 29 June. Payments will be made into nominated bank accounts on Saturday 1 July.
2016/17 payment summaries
  • Access to payment summaries for the 2016/17 financial year will be available (to all current staff) via ESS from Monday 3 July.
  • Staff members who have resigned from Monash will receive their payment summary in the mail. Payment summaries will be posted to the mailing address recorded in the HR system as at Friday 23 June.
  • FAQs on viewing or reading information displayed on payment summaries are available from ask.monash.

For further information on any of the above payroll activities, please contact Access HR on 03 99020400.

Monash lupus research receives donation from Lupus Victoria

A generous donation from Lupus Victoria will fund a Monash University PhD scholarship, enabling vital research into lupus.

Lupus Victoria, a charity supporting research into systemic lupus erythematosus, or lupus, has donated $26,000 to the School of Clinical Sciences at Monash Health (SCS), directly supporting the Kim Jolly Lupus Research Fund Scholarship.

PhD student and Monash Health Rheumatology Fellow Dr Champa Nataraja is the first recipient of the scholarship—her research aiming to improve outcomes for patients with lupus.

“Lupus is a chronic, multi-system autoimmune disease affecting at least 5 million people worldwide, with the majority being women of childbearing age,” Dr Nataraja said.

“Over 70 per cent of patients with lupus are typically treated with glucocorticoids (GC) due to their broad anti-inflammatory effect, however, despite their effectiveness, the use of these drugs is accompanied by a litany of serious adverse effects that contribute to increased morbidity and mortality.”

Dr Nataraja said there is a critical need for alternative therapies to GC that have similar anti-inflammatory effects but without the negative metabolic side-effects.

Under the supervision of Dr Sarah Jones and Professor Eric Morand from the Lupus and Arthritis Research Group, Dr Nataraja is investigating glucocorticoid-induced leucine zipper (GILZ), a protein induced by GC that may lead to an alternative therapy.

“My PhD will validate GILZ as a therapeutic target in lupus, potentially leading to improved therapies and outcomes for patients,” Dr Nataraja said.

I feel honoured and privileged to be the first recipient of The Kim Jolly Lupus Research Fund Scholarship and am grateful this scholarship facilitates me to continue with this vital research project.”

Head of the Lupus and Arthritis Research Group Professor Morand said he is honoured to have the continuing relationship with patients and families affected by lupus, who make up Lupus Victoria, and who share our belief that research is the way we will solve this disease.

“Lupus Victoria were supporters of our work from the start and our growth now to national and international prominence in this field would not have happened without their support at the beginning,” Professor Morand said. 

SCS PhD student Lachlan McMillan selected to attend Stanford SPARK workshop

Lachlan McMillan
School of Clinical Sciences at Monash Health PhD student Lachlan McMillan has received a competitive grant to attend the prestigious Stanford SPARK Biomedical Innovation and Entrepreneurship Course in Tokyo this August.

Established ten years ago and a unique partnership between university and industry, the Stanford SPARK program aims to advance new biomedical research discoveries into promising new treatments for patients.

Lachlan’s PhD is focused on improving bone health in older adults.

“There is currently a crisis in the treatment of osteoporosis, with prescription and adherence to pharmacological regimes at an all-time low,” Lachlan said.

“As such it's imperative we understand how else to best influence bones, in the goal of preventing or attenuating the development of osteoporosis.”

Lachlan is developing a wearable device that will accurately and objectively quantify activity which is most beneficial for bones, i.e. weight-bearing activity such as jumping or hopping.

“We ultimately hope to deploy our device to research institutions around the world who are investigating the effect of physical activity on a range of outcomes, delivering a commercial result.”

Some of the benefits Lachlan hopes to gain from the SPARK program include a much greater understanding of innovation and development in medical technology in fields outside his area of research.

“I hope that I'll get a better understanding of the key medical problems currently being addressed, and how the process works,” Lachlan said.

“I also expect that networking with researchers and medical innovation experts from all over the world will provide me with a unique opportunity to learn from people with varied backgrounds, hopefully leading to future cross-institutional collaborations.”

New SCS website now live

The School of Clinical Sciences at Monash Health (SCS) has a new-look website, and is now consistent with the University's new templates.

Visit our new site here:  https://www.monash.edu/medicine/scs

If you have any questions about the new site or require updates, please contact Vithya Premkumar (vithya.premkumar@monash.edu)

Miltenyi Cell Therapy Day at MHTP, 14 July

All staff and students are invited to the Miltenyi Biotec Australia Cell Therapy Day meeting at MHTP:

Friday July 14,  10:00 a.m. – 06:00 p.m.
Translational Research Facility, MHTP

Cell therapy has the potential to increase antitumor immunity, enhance vaccine efficacy, and limit graft-versus-host disease (GvHD).  At this Australia-first event, key opinion leaders from Australia and New Zealand will discuss and share newest information on adoptive immunotherapies and stem cell therapies, including gene manipulation. Participants are from all parts of Australia, including academic researcher and biotech industry, providing an ideal networking opportunity.

Please email hermannb@miltenyibiotec.com.au or macs@miltenybiotec.com.au to register your attendance.

Program below:

10:00 a.m. – Welcome
Graham Jenkin, Monash Health Translation Precinct Cell Therapies Platform, Melbourne
Hermann Bohnenkamp, Miltenyi Biotec Pty Ltd., Sydney

10:10 a.m. Introduction
John Rasko, Royal Prince Alfred Hospital, Sydney

10:15 – 11:20 a.m. Session 1: Adoptive T cell therapies
Cell banks for therapy of viral and fungal infections: the case for depersonalised medicine
David Gottlieb, The Westmead Institute for Medical Research, Sydney
“Off-the-Shelf” Cellular immune therapies: Driving success with post-transplant lymphomas to infectious
complications and virus-associated cancers
Rajiv Khanna, QIMR Berghofer Medical Research Institute, Brisbane
Making immunotherapy simpler and cheaper to deliver using 3D lattices
Simon Barry, University of Adelaide, Adelaide
Morning tea

11:50 – 01:00 p.m. Session 2: Stem cell therapies
TCR α+β+/CD19+ cell depleted haploidentical donor stem cell transplantation for paediatric patients
Richard Mitchell, Sydney Children's Hospital, Sydney
Engraftment of gene-modified HSCs: One shot?
Geoff Symonds, Calimmune Pty Ltd., Sydney
Stem cells and gene editing in clinical medicine
Alan Trounson, Cartherics Pty Ltd., Melbourne

Lunch break

2:00 – 3:30 p.m. Session 3: Gene-modified T cell therapies
Improving T cell therapy with safety switch and gene marking
Siok Tey, QIMR Berghofer Medical Research Institute, Brisbane
Update on CARPETS Phase 1 Study of GD2-specific CAR T cell therapy for metastatic melanoma
Michael Brown, Centre for Cancer Biology, University of South Australia, Adelaide
New strategies for enhancing CAR T cell therapy for cancer
Phil Darcy, Peter MacCallum Cancer Centre, Melbourne
Transposon CAR T cells for Australia
Ken Micklethwaite, The Westmead Institute for Medical Research, Sydney

Afternoon Tea

4:00 – 4:30 p.m. Session 4: Technology update for cell manufacturing
Novel aspects of sorting in a closed System: Update on the MACSQuant® Tyto™
Jack Dunne, Owl Biomedical, Santa Barbara, CA, USA

5:00 p.m. Practical demonstration of the MACSQuant Tyto and the CliniMACS Prodigy®*
* To attend the demonstration, please register on-site.

MHTP Technical Seminar "Introducing the new Functional Genomics Capability "Pooled CRISPR Screening: What It Can Do For You", Wednesday 21st June

Presenter: Catherine Itman, MHTP Functional Genomics Capability Manager
Location: Seminar room 1, Level 2, TRF Building.
Date: Wednesday 21st June at 11:00am-12:00pm

Learn about how pooled CRISPR library screens are performed and analyzed, and their value in identifying novel target genes involved in a variety of cellular activities. Information will be provided on the types of screens available from the MHTP Functional Genomics Capability and how pooled screens channel into other Platforms and Capabilities within the MHTP-Monash Precinct

Monash Haematology Journal Club: “Venous Thromboembolism in Cancer”, 21 June

7.30am Breakfast & 7.45am Presentation
Monash Medical Centre, Level 2 - Lecture Theatre 3

Presenter: Dr Ming Sheng Lim 

Falling Walls Lab Australia 2017 - DEADLINE EXTENDED

The Australian Academy of Science (AAS) invites applications from Australian, New Zealand and Pacific Island Forum (PIF) Nations researchers, postdocs and students, entrepreneurs, engineers and innovators from all areas to attend the Falling Walls Lab Australia 2017. Extended deadline for applications is 5pm (AEST) Monday 26 June 2017.

20 Australian and 5 New Zealand/PIF Nations contestants will be invited to participate in this challenge with each required to give a 3 minute presentation on their research, business model or initiative based on the “Which walls will fall next” concept.

Candidates should be research active in any field of the natural sciences, including technology, engineering and medicine as well as social sciences and humanities.

See the website for the application forms and further details.

Eligibility Requirements
Applicants must be either:
·  an Australian or New Zealand citizen
·  an Australian permanent resident or hold a valid student or working visa
·  a New Zealand permanent resident or hold a valid student or working visa
·  a citizen or resident of a PIF Nation outside Australia and New Zealand
You must be based in either Australia, New Zealand, or a PIF Nation at the time of application.
You must be 18 years of age or over
You must be currently enrolled in university or hold a degree (copy of degree may be required).

Applicants must either:
·  hold a bachelor’s degree which must have been received within ten (10) years prior to 1 January 2017 (i.e. conferred on or after 1 January 2007)
·  hold a master’s degree which must have been received within seven (7) years prior to 1 January 2017 (i.e. conferred on or after 1 January 2010)
·  hold a PhD which must have been received within five (5) years prior to 1 January 2017 (i.e. conferred on or after 1 January 2012)

Applicants must hold a passport valid until at least April 2018.

Submission Process
Applications are to be submitted by the researchers directly to the funder.

PURE records must be submitted ahead of the funder's submission date for School and Faculty approval.
Funding Opportunity: Falling Walls Lab Australia
Funder: Australian Academy of Science

​For questions about the scheme, please contact MRO (​mro-applications@monash.edu).